“A new Ipsos poll conducted on behalf of MDVIP finds most Americans would like to take steps to live healthier for longer, but few are knowledgeable about the different risk factors that could prevent them from doing so”.-  IPSOS

Biohacking blends science, self-experimentation, and clinical insight to improve performance at the cellular level. For patients, that means more energy, sharper focus, better sleep, and slower biological aging.

What Is Biohacking?

At its core, biohacking involves making small, strategic changes to improve biology and extend healthspan. This may include:

• Enhancing mitochondrial function

• Reducing biological age through epigenetic support

• Improving cognitive performance and memory

• Supporting metabolic flexibility

• Optimizing circadian rhythm and recovery

While some view biohacking as tech-heavy or experimental, many evidence-based tools have a strong foundation in functional medicine. The key is combining lifestyle, nutrition, and targeted supplementation to improve resilience and slow aging at the source.

5 Biohacking Strategies for Healthy Aging

1. Mitochondrial Support

Mitochondria power nearly every cell in the body, and their function declines with age. Supporting mitochondrial renewal is foundational to any longevity protocol.

Key supplements:

• CoQ10/Ubiquinol – Supports ATP production and acts as an antioxidant

• PQQ – Promotes mitochondrial biogenesis; may enhance cognition

• Alpha-lipoic acid – Antioxidant and cofactor in mitochondrial metabolism

• Magnesium – Required for mitochondrial enzyme activity

Additional strategies: intermittent fasting, red light therapy, cold exposure

2. Cellular Senescence & NAD+ Restoration

Senescent cells and declining NAD+ levels contribute to inflammation and poor tissue repair.

Recommended tools:

• NMN or NR – NAD+ precursors supporting DNA repair and metabolism

• Resveratrol – Activates sirtuins, promotes cellular resilience

• Fisetin – Has senolytic effects in clearing aging cells

• Quercetin – Supports detox and inflammation reduction

Clinical note: Fasting protocols naturally trigger autophagy and complement these interventions.

3. Circadian Rhythm Optimization

Disrupted sleep-wake cycles can impair hormonal balance, mood, and immune health.

Biohacking strategies:

• Morning sunlight – Regulates circadian clock, enhances serotonin

• Blue light blocking – Preserves melatonin production after sunset

• Melatonin or L-theanine – Improves sleep onset and depth

• Magnesium glycinate – Supports sleep quality and nervous system calm

• Wearables (e.g., Oura, WHOOP) – Help track HRV and REM cycles for personalized insights

-4. Brain Optimization & Cognitive Longevity

Mental clarity and neuroprotection are essential for aging well. Nootropics and neurotrophins play a key role.

Cognitive support supplements:

• Lion’s Mane – Stimulates Nerve Growth Factor (NGF)

• Phosphatidylserine – Supports memory and focus

• Bacopa monnieri – Enhances learning and cognitive speed

• Omega-3s (EPA/DHA) – Protects against neuroinflammation

Pair these with meditation, vagus nerve stimulation, and cognitive training apps like BrainHQ or Lumosity.

5. Metabolic Flexibility & Inflammation Control

A flexible metabolism improves energy, blood sugar control, and immune resilience.

Top tools in practice:

• Berberine – Mimics some effects of metformin; supports glucose regulation

• Curcumin – Powerful anti-inflammatory compound

• Probiotics & Prebiotics – Modulate the gut-brain axis

• Sulforaphane (from broccoli sprouts) – Activates Nrf2, combats oxidative stress
  Learn more about Nrf2 in this article

Why Providers Choose DSS for Biohacking Protocols

With DSS, you can:

• Create personalized dispensary protocols to match each biohacking plan

• Track refill patterns and compliance with ease

• Offer curated formulas from high-quality, practitioner-trusted brands

• Rely on 99.992% shipping accuracy and Uncommonly Good Customer Service

Our platform is built to feel like an extension of your practice—not a distant warehouse.

Final Thoughts

Biohacking isn’t hype—it’s a personalized, patient-centered approach to healthy aging. As a functional medicine provider, you have the expertise to guide patients through it with insight and care.

Let Doctors Supplement Store be your partner in building smarter longevity protocols—so your patients can not only live longer, but thrive while doing it.